If the question asker wants more concrete sources of gene mutation, they can be caused by viruses, chemicals, radiation, and other mutagenic agents.
2.
Brio is the penultimate boss of the first game, transforming himself into a hulking beast ( through use of his trademark mutagenic agent ), to combat Crash.
3.
Likewise, Colostrinin reduced the frequency of mutation caused by two mutagenic agents, methyl methane sulfonate and mitomycin-C, the latter often used in cancer chemotherapy.
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